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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
SCMC1_HUMAN
USC-OGP 2-DE database
:
SCMC1_HUMAN
SCMC1_HUMAN
General information about the entry
View entry in simple text format
Entry name
SCMC1_HUMAN
Primary accession number
Q6NUK1
Secondary accession number(s)
Q9P129
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Calcium-binding mitochondrial carrier protein SCaMC-1; AltName: Full=Mitochondrial ATP-Mg/Pi carrier protein 1; AltName: Full=Mitochondrial Ca(2+)-dependent solute carrier protein 1; AltName: Full=Small calcium-binding mitochondrial carrier protein 1; AltName: Full=Solute carrier family 25 member 24;.
Gene name
Name=SLC25A24
Synonyms=APC1, MCSC1, SCAMC1
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1173
:
pI=5.91; Mw=45157
Cross-references
UniProtKB/Swiss-Prot
Q6NUK1; SCMC1_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
SCMC1_HUMAN
Primary accession number
Q6NUK1
Secondary accession number(s)
B7ZAI9 Q5T331 Q5T485 Q6PJJ9 Q705K4 Q9P129
Sequence was last modified on
February 5, 2008 (version 2)
Annotations were last modified on
March 15, 2017 (version 122)
Name and origin of the protein
Description
RecName: Full=Calcium-binding mitochondrial carrier protein SCaMC-1; AltName: Full=Mitochondrial ATP-Mg/Pi carrier protein 1; AltName: Full=Mitochondrial Ca(2+)-dependent solute carrier protein 1; AltName: Full=Small calcium-binding mitochondrial carrier protein 1; AltName: Full=Solute carrier family 25 member 24;
Gene name
Name=SLC25A24
Synonyms=APC1, MCSC1, SCAMC1
Encoded on
Name=SLC25A24; Synonyms=APC1, MCSC1, SCAMC1
Keywords
3D-structure
;
Acetylation
;
Alternative splicing
;
Calcium
;
Complete proteome
;
Membrane
;
Metal-binding
;
Mitochondrion
;
Mitochondrion inner membrane
;
Reference proteome
;
Repeat
;
Transmembrane
;
Transmembrane helix
;
Transport
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AJ619987; CAF04493.1
; -; mRNA
EMBL
AJ619961; CAF04058.1
; -; mRNA
EMBL
AK292567; BAF85256.1
; -; mRNA
EMBL
AK316304; BAH14675.1
; -; mRNA
EMBL
AL390036; CAI13622.1
; ALT_SEQ; Genomic_DNA
EMBL
AL359258; CAI13622.1
; JOINED; Genomic_DNA
EMBL
AL390036; CAI13623.1
; -; Genomic_DNA
EMBL
AL359258; CAI13623.1
; JOINED; Genomic_DNA
EMBL
AL359258; CAI14512.1
; ALT_SEQ; Genomic_DNA
EMBL
AL390036; CAI14512.1
; JOINED; Genomic_DNA
EMBL
AL359258; CAI14513.1
; -; Genomic_DNA
EMBL
AL390036; CAI14513.1
; JOINED; Genomic_DNA
EMBL
CH471156; EAW51254.1
; -; Genomic_DNA
EMBL
CH471156; EAW51255.1
; -; Genomic_DNA
EMBL
BC014519; AAH14519.1
; -; mRNA
EMBL
BC068561; AAH68561.1
; -; mRNA
EMBL
AF123303; AAF28888.1
; ALT_FRAME; mRNA
CCDS
CCDS41361.1; -. [Q6NUK1-1]
; .
CCDS
CCDS786.1; -. [Q6NUK1-2]
; .
RefSeq
NP_037518.3; NM_013386.4. [Q6NUK1-1]
; .
RefSeq
NP_998816.1; NM_213651.2. [Q6NUK1-2]
; .
UniGene
Hs.656870; -
; .
PDB
4N5X; X-ray
; 2.10 A; A=1-193
PDB
4ZCU; X-ray
; 2.10 A; A/B/C=14-174
PDB
4ZCV; X-ray
; 2.80 A; A/B/C/D=14-174
PDBsum
4N5X; -
; .
PDBsum
4ZCU; -
; .
PDBsum
4ZCV; -
; .
ProteinModelPortal
Q6NUK1; -
; .
SMR
Q6NUK1; -
; .
BioGrid
118993; 29
; .
IntAct
Q6NUK1; 5
; .
MINT
MINT-4905805; -
; .
STRING
9606.ENSP00000457733; -
; .
TCDB
2.A.29.23.8; the mitochondrial carrier (mc) family
; .
iPTMnet
Q6NUK1; -
; .
PhosphoSitePlus
Q6NUK1; -
; .
SwissPalm
Q6NUK1; -
; .
BioMuta
SLC25A24; -
; .
DMDM
167016554; -
; .
EPD
Q6NUK1; -
; .
MaxQB
Q6NUK1; -
; .
PaxDb
Q6NUK1; -
; .
PeptideAtlas
Q6NUK1; -
; .
PRIDE
Q6NUK1; -
; .
TopDownProteomics
Q6NUK1-1; -. [Q6NUK1-1]
; .
TopDownProteomics
Q6NUK1-2; -. [Q6NUK1-2]
; .
DNASU
29957; -
; .
Ensembl
ENST00000370041; ENSP00000359058
; ENSG00000085491. [Q6NUK1-2]; .
Ensembl
ENST00000565488; ENSP00000457733
; ENSG00000085491. [Q6NUK1-1]; .
GeneID
29957; -
; .
KEGG
hsa:29957; -
; .
UCSC
uc001dvm.5; human. [Q6NUK1-1]
; .
CTD
29957; -
; .
DisGeNET
29957; -
; .
GeneCards
SLC25A24; -
; .
H-InvDB
HIX0000832; -
; .
H-InvDB
HIX0023826; -
; .
HGNC
HGNC:20662; SLC25A24
; .
HPA
HPA028519; -
; .
HPA
HPA063636; -
; .
MIM
608744; gene
; .
neXtProt
NX_Q6NUK1; -
; .
OpenTargets
ENSG00000085491; -
; .
PharmGKB
PA134978257; -
; .
eggNOG
KOG0036; Eukaryota
; .
eggNOG
ENOG410XQ4P; LUCA
; .
GeneTree
ENSGT00760000119245; -
; .
HOVERGEN
HBG108464; -
; .
InParanoid
Q6NUK1; -
; .
KO
K14684; -
; .
OMA
TTWLEHY; -
; .
OrthoDB
EOG091G0C8S; -
; .
PhylomeDB
Q6NUK1; -
; .
TreeFam
TF313492; -
; .
ChiTaRS
SLC25A24; human
; .
GenomeRNAi
29957; -
; .
PRO
PR:Q6NUK1; -
; .
Proteomes
UP000005640; Chromosome 1
; .
Bgee
ENSG00000085491; -
; .
CleanEx
HS_SLC25A24; -
; .
ExpressionAtlas
Q6NUK1; baseline and differential
; .
Genevisible
Q6NUK1; HS
; .
GO
GO:0016021; C:integral component of membrane
; IDA:UniProtKB; .
GO
GO:0005743; C:mitochondrial inner membrane
; IBA:GO_Central; .
GO
GO:0005739; C:mitochondrion
; IDA:UniProtKB; .
GO
GO:0015217; F:ADP transmembrane transporter activity
; IBA:GO_Central; .
GO
GO:0005347; F:ATP transmembrane transporter activity
; IMP:UniProtKB; .
GO
GO:0005509; F:calcium ion binding
; IDA:UniProtKB; .
GO
GO:0015867; P:ATP transport
; IMP:UniProtKB; .
GO
GO:0071277; P:cellular response to calcium ion
; IMP:UniProtKB; .
GO
GO:0034599; P:cellular response to oxidative stress
; IMP:UniProtKB; .
GO
GO:0006839; P:mitochondrial transport
; IMP:UniProtKB; .
GO
GO:0010941; P:regulation of cell death
; IMP:UniProtKB; .
CDD
cd00051; EFh
; 2; .
Gene3D
1.10.238.10; -
; 1; .
Gene3D
1.50.40.10; -
; 1; .
InterPro
IPR011992; EF-hand-dom_pair
; .
InterPro
IPR018247; EF_Hand_1_Ca_BS
; .
InterPro
IPR002048; EF_hand_dom
; .
InterPro
IPR002167; Graves_DC
; .
InterPro
IPR002067; Mit_carrier
; .
InterPro
IPR018108; Mitochondrial_sb/sol_carrier
; .
InterPro
IPR023395; Mt_carrier_dom
; .
Pfam
PF13499; EF-hand_7
; 2; .
Pfam
PF00153; Mito_carr
; 3; .
PRINTS
PR00928; GRAVESDC
; .
PRINTS
PR00926; MITOCARRIER
; .
SMART
SM00054; EFh
; 3; .
SUPFAM
SSF103506; SSF103506
; 1; .
SUPFAM
SSF47473; SSF47473
; 1; .
PROSITE
PS00018; EF_HAND_1
; 3; .
PROSITE
PS50222; EF_HAND_2
; 4; .
PROSITE
PS50920; SOLCAR
; 3; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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